N-Iodosuccinimide

N-iodosuccinimide (NIS) is an iodine reagent used in organic synthesis for selective iodination, oxidative transformations and halogenation reactions. At Iofina, we provide high-purity N-iodosuccinimide to meet the demands of research and industrial applications. As a reactive compound, it requires careful handling and proper storage to ensure safety.

What Is N-Iodosuccinimide?

N-iodosuccinimide is a white to off-white crystalline solid that is also known as:

1-iodo-pyrrolidine-2,5-dione

1-iodoazolidine-2,5-dione

Succiniodimide

This organic compound is an electrophilic iodinating agent in chemical syntheses. It consists of a succinimide backbone bonded to an iodine atom, making it an effective and controlled source of iodine. Unlike elemental iodine, it provides greater precision in iodine transfer, which is particularly useful in pharmaceutical research, agrochemical development and material science. Due to its stability and predictable reactivity, N-iodosuccinimide has become a preferred alternative to more aggressive halogenating agents. It is sensitive to moisture and heat, requiring dry, airtight storage to maintain its effectiveness.

Applications of N-Iodosuccinimide

N-iodosuccinimide is used in various industries for many applications, which include:

Pharmaceutical synthesis: Researchers use N-iodosuccinimide to introduce iodine into drug molecules, enhancing bioavailability and therapeutic properties.

Agrochemical production: N-iodosuccinimide plays a role in formulating iodine-based pesticides and herbicides that improve crop protection. The introduction of iodine can improve the effectiveness of these compounds.

Halogenation reactions: Chemists apply N-iodosuccinimide in selective halogenation processes, creating key intermediates for various chemical formulations.

Fluorescent labeling: N-iodosuccinimide facilitates the synthesis of iodinated fluorescent probes, which are essential in biomedical imaging and diagnostics.

Why Source N-Iodosuccinimide From Iofina?

Iofina specializes in the extraction and production of iodine, along with the development of various iodine-based chemical derivatives for industries around the world. Sourcing iodine, N-iodosuccinimide and other derivatives from us means committing to:

Eco-friendly extraction: We recover iodine using the most environmentally responsible methods, eliminating the need for destructive drilling or explosions. By partnering with oil companies, we extract iodine from pre-drilled sites. We carefully remove the water from the site to gather the iodine and return it to the well after processing.

Innovative technology: As a leader in iodine processing technology, we develop and refine specialty compounds. Our advanced processing methods recover valuable resources that would otherwise go to waste, making our approach sustainable.

Extensive product line and reach: We supply a diverse range of iodides, chlorides and fluorides for industries like health care, biocides and animal nutrition. As one of North America’s largest iodine producers, we serve global markets and offer expert technical support.

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